Test-tube model of breast cancer to replace animal experiments
01. 04. 2009 | Cancer Research UKAn award-winning team of UK scientists has developed a three-dimensional (3-D) model of human breast cancer in a test-tube which should help to reduce the number of animals used and improve the quality of cancer research [1].
Image by Philippe Delavie from Pixabay
Animals play a vital role during research into new drugs, but scientists are constantly looking for ways to replace them in medical experiments.
Now, a team of scientists at Queen Mary's, University of London, has developed a 3-D model of ductal carcinoma in situ (DCIS), a condition where cells inside the ducts of the breast have started to become cancerous but have not yet invaded the rest of the breast.
Read the whole article at Cancer Research UK
Reference
- Holliday DL, Brouilette KT, et al. Novel multicellular organotypic models of normal and malignant breast: tools for dissecting the role of the microenvironment in breast cancer progression. Breast Cancer Reseach 2009; 11(1): R3. doi: 10.1186/bcr2218
klíčová slova: cancer research, three-dimensional model, breast cancer
