Men with faulty gene may carry breast cancer risk
06. 07. 2010 | ecancer.orgMen who carry a faulty BRCA2 gene have a 1 in 15 chance of developing breast cancer by the time they reach 70, suggests the largest study of its kind, published online in the Journal of Medical Genetics [1].
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Carriage of a faulty BRCA2 gene in women significantly increases their chances of developing breast cancer, and often at a young age. But it has not been clear whether men are susceptible, largely because few studies have been carried out, and published research has been based on retrospective data.
In the current study the research team used both retrospective and prospective data from 321 families with a faulty BRCA2 gene.
Read the whole article at ecancer.org
Reference
- Evans DG, Susnerwala I, et al. Risk of breast cancer in male BRCA2 carriers. Journal of Medical Genetics 2010; 47(10):710-711. doi: 10.1136/jmg.2009.075176.
klíčová slova: BRCA2, breast cancer, men
